Cast

• Henry Fonda Frank
• Claudia Cardinale Jill McBain
• Jason Robards Cheyenne
• Charles Bronson Harmonica
• Gabriele Ferzetti Morton (railroad baron)
• Paolo Stoppa Sam
• Woody Strode Stony (member of Frank's gang)
• Jack Elam Snaky (member of Frank's gang)
• Keenan Wynn Sheriff (auctioneer)
• Frank Wolff Brett McBain
• Lionel Stander Barman
• Livio Andronico Bit part (uncredited)
• Salvatore Basile Bit part (uncredited)
• Aldo Berti Member of Frank's gang playing poker (uncredited)
• Frank Braña Mamber of Frank's gang smoking pipe at auction (uncredited)
• Marilù Carteny Maureen McBain (uncredited)
• Saturno Cerra Hired Gun on Train (uncredited)
• Luigi Ciavarro Older sheriff's deputy (uncredited)
• Spartaco Conversi Member of Frank's gang shot through boot (uncredited)
• Bruno Corazzari (uncredited)
• Paolo Figlia (uncredited)
• John Frederick Jim (member of Frank's gang) (uncredited)
• Don Galloway Member of Frank's Gang in flashback (uncredited)
• Michael Harvey Frank's lieutenant (uncredited)
• Stefano Imparato (uncredited)
• Frank Leslie (uncredited)
• Luigi Magnani (uncredited)
• Claudio Mancini Harmonica's brother (uncredited)
• Umberto Marsella (uncredited)
• Dino Mele Harmonica, as a boy (uncredited)
• Antonio Molino Rojo Member of Frank's gang at auction (uncredited)
• Enrico Morsella (uncredited)
• Al Mulock Knuckles (uncredited)
• Tullio Palmieri Flagstone carpenter (uncredited)
• Renato Pinciroli First bidder at auction (uncredited)
• Lorenzo Robledo 2nd Member of Cheyenne's Gang (uncredited)
• Sandra Salvatori (uncredited)
• Aldo Sambrell Cheyenne's lieutenant (uncredited)
• Conrado San Martín Gangmember on Train (uncredited)
• Enzo Santaniello Timmy McBain (uncredited)
• Simonetta Santaniello (uncredited)
• Claudio Scarchilli (uncredited)
• Giovanni Ivan Scratuglia (uncredited)
• Robert Spafford Construction yard owner (uncredited)
• Benito Stefanelli Frank's lieutenant (uncredited)
• Luana Strode Indian woman (uncredited)
• Fabio Testi Member of Frank's gang with black hat at auction (uncredited)
• Dino Zamboni (uncredited)
• Marco Zuanelli Wobbles (uncredited)

Writers

• Dario Argento
• Bernardo Bertolucci
• Sergio Leone
• Sergio Leone
• Sergio Donati
• Mickey Knox

Producers

• Bino Cicogna
• Fulvio Morsella